Protein Alignment CG33458 and ACR

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 130/319 - (40%)
• Gaps: 67/319 - (21%)

  Fly     1 MKLIPALLALLILGHGISLGYSYLLEWDCGI-----SKYTYRITGGRDSPLMLNPWLAYLHI--- 57
            ::::|..: ||:|...:....:...:..||:     .:...||.||:.:.....||:..|.|
Human     2 VEMLPTAI-LLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTY 65

  Fly    58 NSK--FICGGSLLNHWFVLTAAHCFRDKNAKVLVRL--GENDASQKIDCNESECAAPHLEYMIMQ 118
            ||.  ..|||||||..:||||||||..||.....||  |..:.:..   |.....||..|..:.:
Human    66 NSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYG---NNKPVKAPLQERYVEK 127

  Fly   119 KLIHPLYRTA-HYYDIALAKLNRYVVYTDSIRPICLMLNPN------------WQVYVDTIRYFI 170
            .:||..|.:| ...||||.::...:.....|.|.||   |:            |
Human   128 IIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCL---PHFKAGLPRGSQSCW----------- 178

  Fly   171 ITGWG--ATNASEVSDKLQLTRIPQIDRFTCR--YWFGYMVDRTHICAGESKHYVGK-----GDS 226
            :.|||  ...|...|..|...|:..||...|.  .|:...|..|::|||   :.|||     |||
Human   179 VAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAG---YPVGKIDTCQGDS 240

  Fly   227 GGPLGSMVDYKYAKRFFQFGIVS------HLRQPFHGVSVFTNILSYSNWIHRTIITNS 279
            ||||  |........:...||.|      ..::|    .::|....|.|||...|.:|:
Human   241 GGPL--MCKDSKESAYVVVGITSWGVGCARAKRP----GIYTATWPYLNWIASKIGSNA 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	83/270 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	82/268 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421