Protein Alignment CG33458 and KLK2

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 77/287 - (26%)
• Similarity: 120/287 - (41%)
• Gaps: 49/287 - (17%)

  Fly    11 LILGHGISLGYSYLLEWDC--GISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFV 73
            |:|...:|:|        |  .:.....||.||.:......||...::.:....|||.|::..:|
Human     4 LVLSIALSVG--------CTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60

  Fly    74 LTAAHCFRDKNAKVLVRLGEN------DASQKIDCNESECAAPHLEY---MIMQKLIHPLYRTAH 129
            ||||||.: ||::|.  ||.:      |..|::..:.|   .||..|   ::..:.:.|...::|
Human    61 LTAAHCLK-KNSQVW--LGRHNLFEPEDTGQRVPVSHS---FPHPLYNMSLLKHQSLRPDEDSSH 119

  Fly   130 YYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGATNASEV--SDKLQLTRIP 192
              |:.|.:|:.....||.::.:.|   |..:..:.|..|  .:|||:....|.  ...||...:.
Human   120 --DLMLLRLSEPAKITDVVKVLGL---PTQEPALGTTCY--ASGWGSIEPEEFLRPRSLQCVSLH 177

  Fly   193 QIDRFTCRYWFGYMVDRTHICAG---ESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSHLRQP 254
            .:....|...:...|....:|||   ..|...| |||||||       ......| ||.|...:|
Human   178 LLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCG-GDSGGPL-------VCNGVLQ-GITSWGPEP 233

  Fly   255 F---HGVSVFTNILSYSNWIHRTIITN 278
            .   ...:|:|.::.|..||..||..|
Human   234 CALPEKPAVYTKVVHYRKWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	68/252 (27%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	68/252 (27%)