Protein Alignment CG33458 and PRSS48

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 93/301 - (30%)
• Similarity: 138/301 - (45%)
• Gaps: 72/301 - (23%)

  Fly     6 ALLALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNH 70
            |...||:||..:           ||...|:.|:.||:|:.....||...||.:..|||||||::.
Human     7 AFTLLLLLGISV-----------CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSE 60

  Fly    71 WFVLTAAHCFRD--KNAKVLVRLGE---NDASQKIDCNESECAAPHLEYMIMQKLIHPLYR--TA 128
            ..:||||||.:.  ......|.||.   .|:.:::            :|.:.:.:|||.|:  ||
Human    61 RLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRV------------KYYVSKIVIHPKYQDTTA 113

  Fly   129 HYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGATNASEVSDK-----LQL 188
               |:||.||:..|.:|.:|.||||   |:....:....:..:||||  ...|.||:     ||.
Human   114 ---DVALLKLSSQVTFTSAILPICL---PSVTKQLAIPPFCWVTGWG--KVKESSDRDYHSALQE 170

  Fly   189 TRIPQIDRFTCRYWFG----------YMVDRTHICAGESKHYVG--KGDSGGPLGSMVDYKYAKR 241
            ..:|.|||..|...:.          .::....||||::::...  ||||||||...:|..:
Human   171 AEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVW--- 232

  Fly   242 FFQFGIVSHLRQPFHGV-------SVFTNILSYSNWIHRTI 275
             .|.|:||      .|:       .|:||::.|..||:.||
Human   233 -IQTGVVS------WGLECGKSLPGVYTNVIYYQKWINATI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	82/266 (31%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	82/266 (31%)