Protein Alignment CG33458 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 77/254 - (30%)
• Similarity: 117/254 - (46%)
• Gaps: 46/254 - (18%)

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRD-KNA-KVLVRLGENDASQK 99
            ||..|..:|....||.|.|..::...||.:|:::.:::||||||:. ||. :..|..|     .|
Human   189 RIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQWTVSFG-----TK 248

  Fly   100 IDCNESECAAPHLEYMIMQKLIHPLYRT-AHYYDIALAKLNRYVVYTDSIRPICL-----MLNPN 158
            |:       .|.::..:.:.:||..||: |..||||:.:::..|.::|.||.|||     ...||
Human   249 IN-------PPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASASFQPN 306

  Fly   159 WQVYVDTIRYFIITGWGAT-NASEVSDKLQLTRIPQIDRFTCR--YWFGYMVDRTHICAG--ESK 218
            ..|:        |||:||. ...|..:.|:..|:..|....|:  ..:|..:.....|||  |..
Human   307 LTVH--------ITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGI 363

  Fly   219 HYVGKGDSGGPLGSMVDYKYAKRFFQFGIVS------HLRQPFHGVSVFTNILSYSNWI 271
            :...:|||||||   |.......::..||||      ...:|    .|:|.:..|.|||
Human   364 YDACRGDSGGPL---VTRDLKDTWYLIGIVSWGDNCGQKDKP----GVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	76/253 (30%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	76/253 (30%)