DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and f10

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	260	Identity:	70/260 - (26%)
Similarity:	119/260 - (45%)	Gaps:	48/260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYL-HINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGEND----- 95
            ||..|.:.|....||.|.| :.|:...|||::|...|:|:||||. :::..:.|.:||.|
Zfish   244 RIVNGVECPPGDCPWQALLINENNMGFCGGTILTEHFILSAAHCM-NESLSIRVVVGEYDTLVPE 307

  Fly    96 ---ASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHYY-DIALAKLNRYVVYTDSIRPICLMLN 156
               |:..:|                :.|||..|:...|: ||||.||::.:.:|..|.|.||
Zfish   308 GREATHDVD----------------EILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACL--- 353

  Fly   157 PNWQVYVDTIRY----FIITGWGATNASEVSDK-LQLTRIPQIDRFTCRYWFGYMVDRTHICAG- 215
            |..: :.:.:..    .:::|:|......:|.. ||...:|.::|..|.....:.:.....|||
Zfish   354 PEMK-FAERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGY 417

  Fly   216 -ESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSH----LRQPFHGVSVFTNILSYSNWIHRTI 275
             :.:....:||||||..:    ::...:|..|:||.    .|:..:|  |:|.:..|..||:..:
Zfish   418 DQEEKDACQGDSGGPHVT----RFKNTWFITGVVSWGEGCARKGKYG--VYTQVSKYIMWINNAM 476

Fly 276 275
Zfish 477 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	68/254 (27%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	69/256 (27%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	68/254 (27%)
		Tryp_SPc	245..474	CDD:238113	69/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010