DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and F9

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	257	Identity:	74/257 - (28%)
Similarity:	118/257 - (45%)	Gaps:	37/257 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKID 101
            |:.||.|:.....||...|:......||||::|..:::|||||. :...|:.|..||:      :
Human   226 RVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV-ETGVKITVVAGEH------N 283

  Fly   102 CNESECAAPHLEYM--IMQKLIHPLYRTA---HYYDIALAKLNRYVVYTDSIRPICLMLNPNWQV 161
            ..|:|    |.|..  :::.:.|..|..|   :.:||||.:|:..:|....:.|||:.    .:.
Human   284 IEETE----HTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIA----DKE 340

  Fly   162 YVDTIRYF---IITGWGAT-NASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVG 222
            |.:....|   .::|||.. :....:..||..|:|.:||.||.....:.:.....|||  .|..|
Human   341 YTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAG--FHEGG 403

  Fly   223 K----GDSGGPLGSMVDYKYAKRFFQFGIVSHLRQ-PFHG-VSVFTNILSYSNWI-HRTIIT 277
            :    ||||||..:.|:    ...|..||:|...: ...| ..::|.:..|.||| .:|.:|
Human   404 RDSCQGDSGGPHVTEVE----GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	70/248 (28%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	71/251 (28%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	71/250 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010