DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33458 and Proc

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	262	Identity:	82/262 - (31%)
Similarity:	117/262 - (44%)	Gaps:	47/262 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLA-YLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKI 100
            ||..|..:....:||.| .|....|..|||.|::..:|||||||. :...|:.|||||.|..::
Mouse   235 RIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCV-EGTKKLTVRLGEYDLRRR- 297

  Fly   101 DCNESECAAPH--LEYMIMQKLIHPLY-RTAHYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVY 162
                     .|  |:..|.:.|:||.| |::...||||.:|.:....:.:|.||||..|...|..
Mouse   298 ---------DHWELDLDIKEILVHPNYTRSSSDNDIALLRLAQPATLSKTIVPICLPNNGLAQEL 353

  Fly   163 VDTIRYFIITGWGATNASEVSDK-------LQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHY 220
            ....:..::|||| ..:..:.|.       |...|||.:.|..|......:|....:|||    .
Mouse   354 TQAGQETVVTGWG-YQSDRIKDGRRNRTFILTFIRIPLVARNECVEVMKNVVSENMLCAG----I 413

  Fly   221 VG------KGDSGGPLGSMVDYKYAKRFFQFGIVS------HLRQPFHGVSVFTNILSYSNWIHR 273
            :|      .||||||   ||.: :...:|..|:||      |.    :...::|.:.||..|||.
Mouse   414 IGDTRDACDGDSGGP---MVVF-FRGTWFLVGLVSWGEGCGHT----NNYGIYTKVGSYLKWIHS 470

  Fly   274 TI 275
            .|
Mouse   471 YI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	78/256 (30%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	80/258 (31%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011
		FXa_inhibition	163..198	CDD:373209
		Tryp_SPc	236..470	CDD:238113	79/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010