DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and F10

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001229297.1	Gene:	F10 / 14058	MGIID:	103107	Length:	493	Species:	Mus musculus

Alignment Length:	263	Identity:	73/263 - (27%)
Similarity:	131/263 - (49%)	Gaps:	44/263 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYLHIN--SKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQK 99
            ||.|||:......||.|.| ||  ::..|||::||.:::||||||..... :..||:|:.: ::|
Mouse   243 RIVGGRECKDGECPWQALL-INEDNEGFCGGTILNEFYILTAAHCLHQAR-RFKVRVGDRN-TEK 304

  Fly   100 IDCNESECAAPHLEYMIMQKLIHPL---------YRTAHYYDIALAKLNRYVVYTDSIRPICLML 155
            .:.||               ::|.:         .|..:.||||:.:|...:.:..::.|.||.
Mouse   305 EEGNE---------------MVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRMNVAPACLP- 353

  Fly   156 NPNW-QVYVDTIRYFIITGWGATN-ASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAG-ES 217
            ..:| :..:.|.:..|::|:|.|: ....|:.|::..:|.:||.||:....:.:.:...||| |:
Mouse   354 QKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFSITQNMFCAGYEA 418

  Fly   218 K-HYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSH----LRQPFHGVSVFTNILSYSNWIHRTIIT 277
            | ....:||||||..:    ::...::..||||.    .|:..:|  ::|.:.::..||.|::..
Mouse   419 KLEDACQGDSGGPHVT----RFKNTYYVTGIVSWGEGCARKGKYG--IYTKVTTFLKWIDRSMKA 477

  Fly   278 NSG 280
            ..|
Mouse   478 RVG 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	69/252 (27%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	70/254 (28%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:291342
		Tryp_SPc	243..471	CDD:214473	69/252 (27%)
		Tryp_SPc	244..473	CDD:238113	70/253 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010