DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and f7

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	261	Identity:	82/261 - (31%)
Similarity:	114/261 - (43%)	Gaps:	43/261 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVL-VRLGENDASQKI 100
            ||.||.:.|....||...|....|..|||.:....::||||||......|.| :..||:|    :
Zfish   195 RIVGGSECPKGHCPWQVLLKYGEKGFCGGVIYKPTWILTAAHCLEKLKVKFLRIVAGEHD----L 255

  Fly   101 DCNESECAAPHLEYMIM--QKLIHPLY--RTAHYYDIALAKLNRYVVYTDSIRPICLMLNPN--- 158
            :.:|.      .|.:|.  |...||.|  .||. .||||.:|...:||:....|:||.|...
Zfish   256 EVDEG------TEQLIQVDQMFTHPAYVSETAD-SDIALLRLRTPIVYSVYAVPVCLPLREMAER 313

  Fly   159 --WQVYVDTIRYFIITGWGATNASEVSDKLQLTR--IPQIDRFTCRYWFGYMVDRTHICAG--ES 217
              |.|...|     ::|||..:....:.:| |.|  :|:|....|.......:.....|||  |.
Zfish   314 ELWAVSKHT-----VSGWGKRSEDGPTSRL-LRRLLVPRIRTQECVQVSNLTLTSNMFCAGYIEG 372

  Fly   218 KHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSH----LRQPFHGVSVFTNILSYSNWIHRTIITN 278
            :....||||||||.:    :|....|..||||.    .|...:|  ::|.:.:|..||.:|  ||
Zfish   373 RQDSCKGDSGGPLVT----RYRDTAFLLGIVSWGKGCARPGSYG--IYTRVSNYLQWIRQT--TN 429

  Fly   279 S 279
            :
Zfish   430 T 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	77/251 (31%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	78/253 (31%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342
		Tryp_SPc	195..424	CDD:214473	77/251 (31%)
		Tryp_SPc	196..427	CDD:238113	78/253 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010