DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and prss60.1

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	293	Identity:	88/293 - (30%)
Similarity:	125/293 - (42%)	Gaps:	46/293 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IGIAVICCLWRRVQGFQMLLEEDCGIP--HNISERSVNAKLAQNPWMAYLETP--KGFHCSGTLI 66
            :.:|::.|    |||....|.. ||:.  :|.....|||.....||...|.:|  .|..|.|:||
Zfish     7 VSLALLLC----VQGSHSQLNV-CGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLI 66

  Fly    67 NHLFVLTAAHCVPDDLLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFR----HRYYNANDQ 127
            |..:|||||||:|  .:.|..|..:..||        .|:....|.::....    |..||....
Zfish    67 NSEWVLTAAHCLP--RITTSSLLVFLGKT--------TQQGVNTYEINRTVSVITVHPSYNNLTN 121

  Fly   128 TNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANATSK-VLRTMNIDR 191
            .|||.:|.|...|.:.|:|||:|:.|.|.. .|....:|.|.....:...|..:. :|:...|..
Zfish   122 ENDIALLHLSSAVTFSNYIRPVCLAAQNSV-FPNGTSSWITGWGNIQLGVNLPAPGILQETMIPV 185

  Fly   192 QPKETCSEIYG-WNMTFEQICAGNTLSQ----LCSTDSGAPQIRK---MWHNGSDRYVQLGIASR 248
            .|.:.|:.:.| .::|...||||  |.|    .|..|||.|.:.|   :|       ||.||.|.
Zfish   186 VPNDQCNALLGSGSVTNNMICAG--LLQGGRDTCQGDSGGPMVSKQCLVW-------VQSGITSW 241

  Fly   249 VKGQC---QNSGILMDLLSYADWIKRVVRQYGP 278
            ..| |   .:.|:...:..|..||..::.|..|
Zfish   242 GYG-CADPYSPGVYTRVSQYQSWINSIIVQNLP 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	74/241 (31%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	72/238 (30%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	75/251 (30%)
		Tryp_SPc	34..267	CDD:238113	77/253 (30%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910