DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and st14b

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	275	Identity:	65/275 - (23%)
Similarity:	101/275 - (36%)	Gaps:	59/275 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGIPHNISERSVNAKLAQN---PWMAYLE-TPKGFHCSGTLINHLFVLTAAHCVPDDLLITVRLG 89
            ||...:.|.|.|..|.:..   ||...|. ..:|..|..::|::.:::||||||.|
Zfish   615 CGKKPHKSSRIVGGKDSDEGEWPWQVSLHMKTQGHVCGASVISNSWLVTAAHCVQD--------- 670

  Fly    90 EYNTKTKVDCDNHLCQEPFQEYNVDMGFR------------------HRYYNANDQTNDIGMLRL 136
                      ::........::.|.:|..                  |..|:.:...|||.::.|
Zfish   671 ----------NDQFRYSQADQWEVYLGLHNQGETSKSTQRSVLRIIPHPQYDHSSYDNDIALMEL 725

  Fly   137 GRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVW---RETAANATSKVLRTMNIDRQPKETCS 198
            ...|....:|.|||:.....: .|..:..|.|.  |   || .::|...||:...:.......||
Zfish   726 DSPVTLNQNIWPICLPDPTHY-FPAGKSVWITG--WGKLRE-GSDAVPSVLQKAEVRIINSTVCS 786

  Fly   199 EIYGWNMTFEQICAGNTLS---QLCSTDSGAPQIRKMWHNGSDRYVQLGIASRVKGQC---QNSG 257
            ::....:|...|||| .||   ..|..|||.|...   ..|:.|....|:.|...| |   ...|
Zfish   787 KLMDDGITPHMICAG-VLSGGVDACQGDSGGPMSS---IEGNGRMFLAGVVSWGDG-CGRRNRPG 846

  Fly   258 ILMDLLSYADWIKRV 272
            :...:..|..||:.:
Zfish   847 VYTRVTDYRSWIREI 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	59/251 (24%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	57/248 (23%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	60/261 (23%)
		Tryp_SPc	625..861	CDD:238113	61/263 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910