DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and f2

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001015797.1	Gene:	f2 / 548514	XenbaseID:	XB-GENE-481539	Length:	607	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	73/308 - (23%)
Similarity:	124/308 - (40%)	Gaps:	76/308 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EEDCGIPHNISERSV---------------------NAKLAQNPW--MAYLETPKGFHCSGTLIN 67
            |..||:.....::||                     .|:....||  |.:.::|:...|..:|::
Frog   319 EAVCGLRPLFEQKSVEDKGEKELLESYMQGRIVKGETAEPGSAPWQVMLFKKSPQELLCGASLLS 383

  Fly    68 HLFVLTAAHCV----------PDDLLITVRLGEYNTKTKVD-CDNHLCQEPFQEYNVDMGFRHRY 121
            ..:||:||||:          .||:|  ||:|:: .:||.: ....:.|       ::....|..
Frog   384 DRWVLSAAHCIFYPPWDKNYTTDDIL--VRIGKH-FRTKYERATERIAQ-------LERIIVHPK 438

  Fly   122 YNANDQTN-DIGMLRLGRRVEYLNHIRPICIFASNRFQEPID-------------QLTWFTTTVW 172
            ||..:..: ||.:::|.|.|.:.|:|.|:|:...:...:.:.             |.||
Frog   439 YNWKENLDRDIALIQLKRPVAFSNYIHPVCLPTKDTVVKLLAAGYKGRVTGWGNLQETW------ 497

  Fly   173 RETAANATSKVLRTMNIDRQPKETCSEIYGWNMTFEQICAG-----NTLSQLCSTDSGAPQIRKM 232
             .:.|....:.|:.:|:....:|||.......:|....|||     :.....|..|||.|.:.|.
Frog   498 -TSGAQNLPQALQQINLPIVDQETCKSSTNIKVTDNMFCAGYNPEDSKRGDACEGDSGGPFVMKD 561

  Fly   233 WHNGSDRYVQLGIASRVKGQCQNS---GILMDLLSYADWIKRVVRQYG 277
            ...|  |:|||||.|..:| |...   |..:.:.....||.:.|.::|
Frog   562 PDTG--RWVQLGIVSWGEG-CDRDNKYGFYVHVHRMRKWIMKTVEKFG 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	65/258 (25%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	63/255 (25%)
f2	NP_001015797.1	GLA	23..86	CDD:214503
		KR	106..185	CDD:214527
		KR	206..287	CDD:214527
		Thrombin_light	303..349	CDD:370463	5/29 (17%)
		Tryp_SPc	349..598	CDD:214473	64/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910