DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and C1s1

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	281	Identity:	69/281 - (24%)
Similarity:	108/281 - (38%)	Gaps:	45/281 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGI---PHNISERSVN---AKLAQNPWMAYLETPKGFHCSGTLINHLFVLTAAHC---VPDDLLI 84
            ||:   |..:.:|...   ||:...||..:...|:   .||.|||..:||||||.   :.|.|:.
Mouse   431 CGVPTEPFQVHQRIFGGQPAKIENFPWQVFFNHPR---ASGALINEYWVLTAAHVLEKISDPLMY 492

  Fly    85 TVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQ-------TNDIGMLRLGRRVEY 142
               :|..:.:|.:       .|..|.......|.|..:...|.       .|||.:::|...|:.
Mouse   493 ---VGTMSVRTTL-------LENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVKM 547

  Fly   143 LNHIRPICI--FASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSEIYGWN- 204
            ...:.|||:  .:|.....|.|.   ...:.|..|........||...:.....|||.::...|
Mouse   548 GPKVSPICLPGTSSEYNVSPGDM---GLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENP 609

  Fly   205 --------MTFEQICAGNTLSQLCSTDSGAPQIRKMWHNGSDRYVQLGIASRVKGQCQNSGILMD 261
                    .|...||||......|..|||.....::.:....::...|:.|..| :|...|:...
Mouse   610 TVRPEDYVFTDNMICAGEKGVDSCHGDSGGAFAFQVPNVTVPKFYVAGLVSWGK-RCGTYGVYTK 673

  Fly   262 LLSYADWIKRVVRQ-YGPSTD 281
            :.:|.|||.:.::: .||..|
Mouse   674 VKNYVDWILKTMQENSGPRKD 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	60/244 (25%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	58/241 (24%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	61/254 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910