DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and AgaP_AGAP012504

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_001231011.2	Gene:	AgaP_AGAP012504 / 4578496	VectorBaseID:	AGAP012504	Length:	839	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	63/263 - (23%)
Similarity:	105/263 - (39%)	Gaps:	40/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 CSGTLINHLFVLTAAHCVPDDLLI---TVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYY 122
            |.|:||...|:||||||..||..:   ..|:|:.|..:..|      .|..|:..:....||..:
Mosquito    49 CGGSLIWENFILTAAHCAADDDNVPPDVARMGDINIYSDED------DEFAQQLKIVEIIRHPKH 107

  Fly   123 NANDQTNDIGMLRLGRRVEYLNHIRPICIFASN--RFQEPIDQLTWFTTTVWRETAANA-TSKVL 184
            ..|....||.:::|.|.|...:.:.|.|::..:  ||.|       .....|..|..:. |:|.|
Mosquito   108 KYNSNYYDIALMKLERNVTLHDTVAPSCLWLDDEIRFPE-------LLAAGWGRTGFDQNTTKTL 165

  Fly   185 RTMNIDRQPKETCSEIYGW-------NMTFEQICAGNTLSQLCSTDSGAPQIRKMWHNGSDRYVQ 242
            ..:.:.....:.||..|..       .:...|.|||:.....|..|||.|...|::.........
Mosquito   166 LKVQLAPITNDKCSTHYQRGVRKLENGLMDHQFCAGDEKMDTCPGDSGGPLHVKLFKEWKLIPFL 230

  Fly   243 LGIASRVKGQC--QNSGILMDLLSYADWIKRVVRQYGP-----------STDMNRSLKKWVDKIP 294
            :|:.|..|. |  ...|:.:.:..:.|||...::::|.           .||...:|:::.:.:.
Mosquito   231 VGVTSFGKA-CGLAAPGVYVKVSKFGDWIIETLQRHGEMATRFKFEPLVCTDRYYNLREYKEDLV 294

  Fly   295 VFY 297
            ..|
Mosquito   295 RVY 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	58/225 (26%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	56/222 (25%)
AgaP_AGAP012504	XP_001231011.2	Tryp_SPc	22..261	CDD:238113	58/225 (26%)
		Tryp_SPc	22..258	CDD:214473	56/222 (25%)
		Trypsin	327..528	CDD:278516
		Tryp_SPc	333..>433	CDD:304450
		Tryp_SPc	611..836	CDD:304450
		Tryp_SPc	611..832	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910