DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and CLIPB19

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_001237510.1	Gene:	CLIPB19 / 4577378	VectorBaseID:	AGAP003247	Length:	367	Species:	Anopheles gambiae

Alignment Length:	275	Identity:	77/275 - (28%)
Similarity:	130/275 - (47%)	Gaps:	41/275 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGIPHNISERSVNAKLAQ---NPWMAYLETPK-----GFHCSGTLINHLFVLTAAHCV---PDDL 82
            ||:..|  .|.:.::..|   .||.|.:|..|     ||||.|||||...:|||||||   |...
Mosquito   106 CGVRTN--TRLIGSQFTQLDDYPWTALIEYEKPDGSTGFHCGGTLINQGHILTAAHCVSTLPAGW 168

  Fly    83 LI-TVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNA--NDQTNDIGMLRLGRRVEYLN 144
            .: .|||||::....:||:.:.|.....:..:.....|..|:|  ...::||.::|..::|.:.:
Mosquito   169 KVHGVRLGEWDLSEALDCELNYCNNAPVDLKISKIMIHEGYDALNGSSSHDIALIRFEQQVNFSD 233

  Fly   145 HIRPIC--IFASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSEIY--GWNM 205
            .|:|||  :..|.|.:...|.::  |...|.::.::|.......:|::.:....||.::  ...:
Mosquito   234 TIKPICLPLAESIRSKNMTDGIS--TVVGWGKSQSSAGVPKRLKLNLNVRDYRVCSALFVRPEEV 296

  Fly   206 TFEQICA--GNTLSQLCSTDSGAPQIRKMWHNGSDRYVQ-----LGIASRVKGQCQNS---GILM 260
            ...|:||  ..:.::|||.||||         |.:|:..     .|||...:.:|...   |:.:
Mosquito   297 QPSQLCALREESNNELCSADSGA---------GLERFFYGFQYLTGIAGSGEHKCGRGNIPGLFV 352

  Fly   261 DLLSYADWIKRVVRQ 275
            .:..|.:||:..||:
Mosquito   353 SVADYVEWIQEKVRE 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	70/248 (28%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	68/245 (28%)
CLIPB19	XP_001237510.1	CLIP	36..89	CDD:288855
		Tryp_SPc	113..361	CDD:214473	70/258 (27%)
		Tryp_SPc	115..364	CDD:238113	71/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810