DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and modSP

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	76/320 - (23%)
Similarity:	116/320 - (36%)	Gaps:	88/320 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WRRVQGFQMLLEEDCG-IPHNISERSVNAKLAQN---PWMAYL-----ETPKGFHCSGTLINHLF 70
            |.|  |.|. .|:||| :...|.:.|.......|   ||...|     |....|.|.|:|:....
  Fly   347 WNR--GRQR-CEQDCGQLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDL 408

  Fly    71 VLTAAHCVPDD-----------LLITVRL----GEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHR 120
            |:||||||.|:           .:|..:.    ||...:.|        :...:...:..|::.|
  Fly   409 VITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEK--------RRDVRLIEIAPGYKGR 465

  Fly   121 ---YYNANDQTNDIGMLRLGRRVEYLNHIRPICI-FASNRFQEPIDQLTWFTTTVWR-------- 173
               ||      .|:.:|.|....|..:.|||||: |||...:|.:..........|.
  Fly   466 TENYY------QDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQ 524

  Fly   174 -ETAANATSKVLRTMNIDRQPKETCSEIYGWNMTFEQICAGNTLSQLCSTDSGAPQIRKM----- 232
             ..|.:.::.|.|....|.|..:.|        .|.|   |.:|:  |..|||.....::
  Fly   525 FVPAVSKSNSVCRRNLRDIQADKFC--------IFTQ---GKSLA--CQGDSGGGFTSELPTNAF 576

  Fly   233 --WHNGSDRYVQLGIASRVKG--QCQNS-GILMDLLSYADWIKRVVRQYGPSTDMNRSLK 287
              |:..  |:...|:.|....  ||.:| .::.::..:.|.|...         ||||::
  Fly   577 STWNTA--RHFLFGVISNAPNADQCAHSLTVMTNIQHFEDMILNA---------MNRSVE 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	61/266 (23%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	60/263 (23%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	4/9 (44%)
		Tryp_SPc	371..616	CDD:214473	61/273 (22%)
		Tryp_SPc	371..591	CDD:304450	56/248 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030