DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and proca

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	312	Identity:	82/312 - (26%)
Similarity:	128/312 - (41%)	Gaps:	75/312 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GIAVIC-CLWRRVQGFQM---------LLEEDCG---IPH------------------NISERSV 40
            |:|..| |    ::|:|:         ..:..||   ||.                  |:.:|
Zfish   145 GLARTCSC----IKGYQLQDNSRKCTPKNDASCGQIRIPKSAYANKPKPVLQPWVMGGNVGKR-- 203

  Fly    41 NAKLAQNPWMAYLETPKG-FHCSGTLINHLFVLTAAHCVPDDLLITVRLGEY------NTKTKVD 98
                .::||.|.:....| |||.|.||:..:|||||||:......:||||:|      .::..:.
Zfish   204 ----GESPWQALILNHLGRFHCGGVLIDENWVLTAAHCLETSSKFSVRLGDYQRFKFEGSEVTLP 264

  Fly    99 CDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQ 163
            ...|:              .|..||.....|||.:|||...|::..:|.|.|:.:....:..:.:
Zfish   265 VKQHI--------------SHPQYNPITVDNDIALLRLDGPVKFSTYILPACLPSLELAKRMLHR 315

  Fly   164 LTWFT-TTVWRETAANATS--KVLRTMNIDRQPKETCSEIYGWNMTFEQICAGNTLSQL---CST 222
            ....| .|.|.:...:|||  ..|..:.:.....:.||.....|::...:||| .|.|:   |..
Zfish   316 NGTVTIITGWGKNNQSATSYNSTLHYVELPIVDNKECSRHMMNNLSDNMLCAG-VLGQVKDACEG 379

  Fly   223 DSGAPQIRKMWHNGSDRYVQLGIASRVK--GQCQNSGILMDLLSYADWIKRV 272
            |||.|.: .::|   |.:..:|:.|..:  ||....||...:.||.|||..|
Zfish   380 DSGGPMM-TLFH---DTWFLVGLVSWGEGCGQRDKLGIYTKVASYLDWIDSV 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	69/238 (29%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	67/235 (29%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342	6/23 (26%)
		Tryp_SPc	195..427	CDD:238113	71/256 (28%)
		Tryp_SPc	197..424	CDD:214473	69/251 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910