DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and CG33465

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	87/303 - (28%)
Similarity:	138/303 - (45%)	Gaps:	25/303 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSNFIIGIAVICCLWRRVQGFQMLLEEDCGIPHNISERSVNAKLAQN-PWMAYLETPKGFHCSGT 64
            :|..:||: |:|      ||...||::.|..|......:.|....:. ||||.:.....|.|.||
  Fly     5 LSLALIGL-VLC------QGLAQLLDKKCHDPKTSENINFNHGATETAPWMASIYKNNQFICDGT 62

  Fly    65 LINHLFVLTAAHCVPDDLLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTN 129
            |::.|||||||.|:..|..:.|..|.||...  |.......|   :|.|.:..:|..:..|:..|
  Fly    63 LVHKLFVLTAASCISKDSQLYVLFGMYNQYR--DASQFFNNE---QYGVAVALQHSNFRPNNGVN 122

  Fly   130 DIGMLRLGRRVEYLNHIRPICIFASNRFQE-PIDQLTWFTTTVWRETAANATSKVLRTMNIDRQP 193
            |||:|||...|.:..|||||||...:..:. |.::...|.   |::....|:|:|.:|:.:.::.
  Fly   123 DIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGFG---WQQQGTEASSQVRQTVYLSQKK 184

  Fly   194 KETC---SEIYGWNMTFEQICAGNTLSQLCSTDSGAPQIRKMWHNGSDRYVQLGIASRVKGQCQN 255
            ...|   .::...|.  .|.||||.....|.::||:|......:...:..||:|:.|.....|..
  Fly   185 PFECHRNGQLLPINE--GQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSP 247

  Fly   256 SGILMDLLSYADWIKRVVRQY---GPSTDMNRSLKKWVDKIPV 295
            :.:..|::::.|||...||.:   |...........|.:.:.|
  Fly   248 TSVYTDVVAFKDWIYNTVRNFETKGDQVVYEECRSNWAEDVLV 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	70/227 (31%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	68/224 (30%)
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	70/227 (31%)
		Tryp_SPc	46..261	CDD:214473	68/224 (30%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463369
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890