DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33462 and f2

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_005169022.1	Gene:	f2 / 325881	ZFINID:	ZDB-GENE-030131-4606	Length:	635	Species:	Danio rerio

Alignment Length:	316	Identity:	78/316 - (24%)
Similarity:	129/316 - (40%)	Gaps:	84/316 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EEDCG---IPHNISERSVN------------------AKLAQNPW--MAYLETPKGFHCSGTLIN 67
            |.|||   :...|::...|                  |::|..||  |.|..:|:...|..:||:
Zfish   343 ELDCGERPLFEKINKADKNEKELLMSYTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLIS 407

  Fly    68 HLFVLTAAHCV---P-------DDLLITVRLGEYN-TKTKVDCDNHLCQEPFQEYNVDMGFRHRY 121
            ..::||||||:   |       :|::  ||||::: ||.:...:..:.        :|....|..
Zfish   408 DEWILTAAHCILYPPWNKNFTINDII--VRLGKHSRTKYERGIEKIVA--------IDEIIVHPK 462

  Fly   122 YNANDQTN-DIGMLRLGRRVEYLNHIRPICI----------FASNRFQEPIDQLTWFTTTVW--- 172
            ||..:..| ||.:|.:.:.|.:.:.|.|:|:          ||..:.:          .|.|
Zfish   463 YNWKENLNRDIALLHMKKPVVFTSEIHPVCLPTKSIAKNLMFAGYKGR----------VTGWGNL 517

  Fly   173 RET-AANATS--KVLRTMNIDRQPKETCSEIYGWNMTFEQICAG-----NTLSQLCSTDSGAPQI 229
            ||: .:|.|:  .||:.:::....:..|.......:|....|||     :.....|..|||.|.:
Zfish   518 RESWTSNPTNLPTVLQQIHLPIVDQSICRNSTSVIITDNMFCAGYQPDDSKRGDACEGDSGGPFV 582

  Fly   230 RKMWHNGSD-RYVQLGIASRVKGQCQNS---GILMDLLSYADWIKRVVRQYGPSTD 281
            .|   :.|| |:.|:||.|..:| |...   |....|.....|:|:|:.:.....|
Zfish   583 MK---SPSDNRWYQIGIVSWGEG-CDRDGKYGFYTHLFRMRRWMKKVIEKTDSGDD 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	68/262 (26%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	66/259 (25%)
f2	XP_005169022.1	GLA	39..100	CDD:214503
		KR	126..206	CDD:214527
		KR	228..309	CDD:214527
		Thrombin_light	326..373	CDD:286482	6/29 (21%)
		Tryp_SPc	373..621	CDD:214473	68/271 (25%)
		Tryp_SPc	374..625	CDD:238113	70/274 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910