DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33462 and f7i

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	287	Identity:	68/287 - (23%)
Similarity:	105/287 - (36%)	Gaps:	73/287 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CG-IPHNISERSVNAKLAQNPWMAYLETPKGFH--------------CSGTLINHLFVLTAAHCV 78
            || ||       |....:||.::..:..|:| |              |.|.|:...:::||||||
Zfish   172 CGKIP-------VQKNTSQNQFLGGIHCPRG-HCPWQVLIDYNGESVCGGALLEGPWLITAAHCV 228

  Fly    79 --PDDLLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVE 141
              .|...:....||::...   .|.  .:||   |.|...|.|..|:.....:|:.:|||...|:
Zfish   229 HQKDTRFLKAVTGEHDLDV---LDG--SEEP---YEVSAVFIHPNYDPETLDSDLALLRLRVPVQ 285

  Fly   142 YLNHIRPICIFASNRFQEPIDQLT--------------WFTTT----VWRETAANA-TSKVLRTM 187
            ...:..|||:        |..||.              |.|.|    :.||..... .|..|:.:
Zfish   286 RSLYAVPICL--------PTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTLQRL 342

  Fly   188 NIDRQPKETCSEIYGWNMTFEQICAGNTLSQ--LCSTDSGAPQIRKMWHNGSDRYVQLGIASRVK 250
            .:...|...|...   |.|....|||.|...  .|....|:|.:.:.   |...:: .|:.|..:
Zfish   343 AVPLLPAAQCGNA---NTTANMFCAGYTEGDHASCRGHDGSPLVTRY---GETSFL-TGVVSWGR 400

  Fly   251 GQCQNSG---ILMDLLSYADWIKRVVR 274
            | |...|   |...:.::..|:..|::
Zfish   401 G-CGPPGYYWIYTKVENFLIWMDTVMK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	60/263 (23%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	59/260 (23%)
f7i	NP_775335.1	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:291342
		Tryp_SPc	188..420	CDD:214473	59/256 (23%)
		Tryp_SPc	188..420	CDD:238113	59/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910