DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33462 and f10

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	260	Identity:	66/260 - (25%)
Similarity:	108/260 - (41%)	Gaps:	48/260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 PWMAYL--ETPKGFHCSGTLINHLFVLTAAHCVPDDLLITVRLGEYNTKTKVDCDNHLCQEPFQ- 109
            ||.|.|  |...|| |.||::...|:|:||||:.:.|.|.|.:|||:|         |..|..:
Zfish   257 PWQALLINENNMGF-CGGTILTEHFILSAAHCMNESLSIRVVVGEYDT---------LVPEGREA 311

  Fly   110 EYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPICI----FASNRFQEPIDQLTWFTTT 170
            .::||....|:.|..:...|||.:::|.:.:::..:|.|.|:    ||.....:..|.|   .:.
Zfish   312 THDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKFAERVLMQQDDGL---VSG 373

  Fly   171 VWRETAANATSKVLRTMNIDRQPKETCSEIYGWNMTFEQICAGNTLSQ--LCSTDSGAPQIRKM- 232
            ..|......:|.:|:.:.:....:..|.|...:.::....|||....:  .|..|||.|.:.:.
Zfish   374 FGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDACQGDSGGPHVTRFK 438

  Fly   233 ----------WHNGSDRYVQLGIASRVKGQCQNSGILMDLLSYADWIKRVVRQYGPSTDMNRSLK 287
                      |..|..|..:.|:.::|.             .|..||...:.:..|.|  ..|||
Zfish   439 NTWFITGVVSWGEGCARKGKYGVYTQVS-------------KYIMWINNAMTKVMPET--GASLK 488

Fly 288 287
Zfish 489 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	61/243 (25%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	59/240 (25%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	59/240 (25%)
		Tryp_SPc	245..474	CDD:238113	61/242 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910