DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and CG30187

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	84/260 - (32%)
Similarity:	122/260 - (46%)	Gaps:	16/260 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GFQMLLEEDCGIPHNISERSV---NAKLAQNPWMAYLETPKGFHCSGTLINHLFVLTAAHCVPDD 81
            |..:.|::.|||  ||:.:..   ||....:.|||.:.....|.|.||||:..||||||||:.|.
  Fly    19 GASIFLDQICGI--NIALKITGGHNAAFQNSVWMAAVHNRTHFICGGTLIHKRFVLTAAHCIVDQ 81

  Fly    82 LLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHI 146
            .:.:|.||.||.....|..:.:.......::|...:.          ||||:|:|...|.:...|
  Fly    82 DVQSVSLGAYNKSDPADRKDVITAVVHSSFDVRASYE----------NDIGLLKLSSDVIFNALI 136

  Fly   147 RPICIFASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSEIYGWNMTFEQIC 211
            |||||..:......:..:..|....|.....|.||.:|:|:.::...:|.|........:.:|||
  Fly   137 RPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYMELSVYPSEKQIC 201

  Fly   212 AGNTLSQLCSTDSGAPQIRKMWHNG-SDRYVQLGIASRVKGQCQNSGILMDLLSYADWIKRVVRQ 275
            ||......|..|||.|....::..| .:|.||.||.|..|..|...|:..||:|:|||||..:.:
  Fly   202 AGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGVYTDLMSFADWIKMTIER 266

Fly 276 275
Fly 267 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	75/224 (33%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	72/221 (33%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	74/234 (32%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960