DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	277	Identity:	74/277 - (26%)
Similarity:	114/277 - (41%)	Gaps:	56/277 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLEEDCGI---PHNI-------SERSV----NAKLAQNPWMAYLE-TPKGFHCSGTLINHLFVLT 73
            ||...|||   ..||       :||.|    .|...:.||.|.|: ...|..|..|||::.::||
Mouse   182 LLNSRCGIRMSSSNIPLPASSSTERIVQGRETAMEGEWPWQASLQLIGAGHQCGATLISNTWLLT 246

  Fly    74 AAHCV-----PDDLLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGM 133
            ||||.     |...::|     :.|         ....|..:.:|.....|..|:.:...|||.:
Mouse   247 AAHCFWKNRDPTKWIVT-----FGT---------TITPPLVKRSVGKIIIHEEYHRDTNENDIAL 297

  Fly   134 LRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCS 198
            .:|..|||:.|.::.:|:..|:....|  :.:.|.|..........|...||...::....:.|:
Mouse   298 AQLTTRVEFSNVVQRVCLPDSSMKLPP--KTSVFVTGFGSIVDDGPTQNKLRQARVETIGSDVCN 360

  Fly   199 --EIYGWNMTFEQICAGNTLSQL--CSTDSGAPQI---RKMWHNGSDRYVQLGIASRVKGQ-C-- 253
              ::|...:|...:|||....::  |..|||.|.:   |.:|      |: :||.|  .|| |
Mouse   361 RKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNRDIW------YI-VGIVS--WGQSCAL 416

  Fly   254 -QNSGILMDLLSYADWI 269
             ...|:...:..|.|||
Mouse   417 PNKPGVYTRVTKYRDWI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	63/239 (26%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	61/237 (26%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	65/252 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910