Protein Alignment CG33462 and F7

DIOPT Version :10

• Sequence 1: NP_995844.2
• Gene: CG33462 / 2768841
• FlyBaseID: FBgn0053462
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 78/295 - (26%)
• Similarity: 121/295 - (41%)
• Gaps: 57/295 - (19%)

  Fly    19 QGFQML---------LEEDCG-IP----HNISE---RSVNAKL---AQNPWMAYLETPKGFHCSG 63
            :|:.:|         :|..|| ||    .|.|:   |.|..|:   .:.||...|.......|.|
Human   205 EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG 269

  Fly    64 TLINHLFVLTAAHCVPDDL-----LITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYN 123
            ||||.::|::||||. |.:     ||.| |||:      |...|...|  |...|........|.
Human   270 TLINTIWVVSAAHCF-DKIKNWRNLIAV-LGEH------DLSEHDGDE--QSRRVAQVIIPSTYV 324

  Fly   124 ANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETA-ANATSKVLRTM 187
            .....:||.:|||.:.|...:|:.|:|:......:..:..:.:...:.|.:.. ..||:..|..:
Human   325 PGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL 389

  Fly   188 NIDRQPKETC---SEIYG--WNMTFEQICAG--NTLSQLCSTDSGAP---QIRKMWHNGSDRYVQ 242
            |:.|...:.|   |...|  .|:|....|||  :.....|..|||.|   ..|..|:       .
Human   390 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWY-------L 447

  Fly   243 LGIASRVKGQCQ---NSGILMDLLSYADWIKRVVR 274
            .||.|..:| |.   :.|:...:..|.:|:::::|
Human   448 TGIVSWGQG-CATVGHFGVYTRVSQYIEWLQKLMR 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	65/242 (27%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	2/10 (20%)
		Tryp_SPc	242..478	CDD:238113	67/253 (26%)