DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	65/292 - (22%)
Similarity:	113/292 - (38%)	Gaps:	64/292 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CLWRRVQGFQMLLEEDCGIPHNISERSV----------NAKLAQNPWMAYLETPKGFH-CSGTLI 66
            |..|.|...:.:   :||:      |||          .|.....||...|.. :|.| |.|::|
  Rat   230 CSSRMVVSLRCI---ECGV------RSVRRQSRIVGGSTASPGDWPWQVSLHV-QGIHVCGGSII 284

  Fly    67 NHLFVLTAAHCVPDDL-----------LITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHR 120
            ...:::||||||.:.|           ::...|..|.::                :.|:....|.
  Rat   285 TPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSLMFYGSR----------------HQVEKVISHP 333

  Fly   121 YYNANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRET-AANATSKVL 184
            .|::..:.|||.:::|...:.:.:.::|:|: .:......:.|..|.:.  |..| ....||.||
  Rat   334 NYDSKTKNNDIALMKLQTPLAFNDVVKPVCL-PNPGMMLDLAQECWISG--WGATYEKGKTSDVL 395

  Fly   185 RTMNIDRQPKETCSEIYGWN--MTFEQICAGNTLSQL--CSTDSGAPQI---RKMWHNGSDRYVQ 242
            ....:.......|:..|.:|  :|...||||.....:  |..|||.|.:   .::|....|....
  Rat   396 NAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNEIWWLIGDTSWG 460

  Fly   243 LGIASRVKGQCQNSGILMDLLSYADWIKRVVR 274
            .|.|     :....|:..::..:.|||.:.:|
  Rat   461 SGCA-----KAYRPGVYGNVTVFTDWIYQQMR 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	55/243 (23%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	53/240 (22%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133	5/25 (20%)
		Tryp_SPc	253..482	CDD:214473	54/253 (21%)
		Tryp_SPc	254..485	CDD:238113	56/255 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910