DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and AgaP_AGAP008911

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_319658.4	Gene:	AgaP_AGAP008911 / 1279878	VectorBaseID:	AGAP008911	Length:	579	Species:	Anopheles gambiae

Alignment Length:	302	Identity:	69/302 - (22%)
Similarity:	126/302 - (41%)	Gaps:	64/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CLW--RRVQGFQMLLEED---CG---IPHNISERSVNAKLAQNPWMAYLETPKG----FHCSGTL 65
            ||:  .:::|    .:||   ||   :..|....:.:|.....||.|.:...||    :.|.|::
Mosquito    14 CLYLVTQIRG----QDEDQLLCGRRKVQTNSMNNNGDAIAGHWPWYAAIYHRKGEKQEYACGGSI 74

  Fly    66 INHLFVLTAAHCV--PDDL----LITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNA 124
            ::...:|||::||  |..:    |:||.:|:.:.|.        .....|.|:|.....|..::.
Mosquito    75 LDETTILTASNCVYTPSGVISAALVTVHVGQIHPKQ--------ASAYAQMYDVREIVVHPGFSE 131

  Fly   125 NDQTNDIGMLRLGRRV----EYLNHIRPICIFASNRFQEPI----DQLTWFTTTVWRETAANATS 181
            ....|||.:::|...:    ||   ::|:|::..:...|.|    ..:..|.....|:.   .:.
Mosquito   132 ASTINDIALIKLTASITLTTEY---VQPVCLWTMDSALELIVGRNGTVVGFGPNERRDV---VSG 190

  Fly   182 KVLRTMNIDRQPKETC----SEIYGWNMTFEQICAGNTLSQ---LCSTDSGAPQIRKMWHNGSDR 239
            :.|:...|.....:||    ..|:|.::..|..| |..|..   .|:.|||    ..::...|.:
Mosquito   191 EQLQQATIGVVDPQTCIASDPAIFGTHLPVETFC-GKGLQNGAGACNGDSG----DGLFFEVSGQ 250

  Fly   240 YVQLGIASRVKGQCQNSG--------ILMDLLSYADWIKRVV 273
            :...|:.:|::...::.|        :..|:..|.|||||.|
Mosquito   251 WFVRGLVARLQPVRESDGLCDPLQYTVYTDVAKYVDWIKRYV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	58/256 (23%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	55/253 (22%)
AgaP_AGAP008911	XP_319658.4	Tryp_SPc	359..573	CDD:304450
		Tryp_SPc	46..290	CDD:238113	58/262 (22%)
		Tryp_SPc	46..288	CDD:214473	56/260 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910