DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and AgaP_AGAP003691

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_313476.4	Gene:	AgaP_AGAP003691 / 1274366	VectorBaseID:	AGAP003691	Length:	831	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	59/244 - (24%)
Similarity:	98/244 - (40%)	Gaps:	54/244 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ETPKGFHCSGTLINHLFVLTAAHCVPDDLL--ITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMG 116
            ||....||.|:||...||||||:|:....:  .|:.:|:||.           ..|.||.::.:.
Mosquito   275 ETGSKRHCYGSLIAPKFVLTAANCLRQYEVDGYTIEMGQYNV-----------YYPVQENSIRVR 328

  Fly   117 FR------HRYYNANDQTNDIGMLRLGRRVEYLNH-IRPICIFASNRFQEPIDQLTWFTTTVWRE 174
            ..      |..::|....||:.:|.:.:.:...|. :.|.||:..::.  |:|:........:.|
Mosquito   329 TEAKKIHYHPEFDAATLANDVALLEIVKPLYTFNKTVLPACIWPWDKL--PVDEYQTNGYVPFNE 391

  Fly   175 TAANA--TSKVLRTMNI-----DRQPKETCSEIYGWNMTFEQICAG--NTLS-QLCSTDSGAPQI 229
            :...:  |::...|.|:     |:.|:             .|.|||  ..|| :.|....|:...
Mosquito   392 SDDESVRTNQFFATANVYDECLDKVPQ-------------HQFCAGFPTALSPKSCHNSVGSAMS 443

  Fly   230 RKMWHNGSDRYVQLGIASRVKGQCQNSG-----ILMDLLSYADWIKRVV 273
            |.::..|  ||.....|...||  :|.|     :...:..|..||..:|
Mosquito   444 RSLYALG--RYFDYIFAINSKG--ENCGFNLPTVYTKIAPYVQWIDSIV 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	58/241 (24%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	56/238 (24%)
AgaP_AGAP003691	XP_313476.4	Tryp_SPc	80..>152	CDD:304450
		Tryp_SPc	276..484	CDD:214473	55/237 (23%)
		Tryp_SPc	281..487	CDD:304450	56/235 (24%)
		CLIP	506..554	CDD:197829
		Tryp_SPc	600..820	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910