DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33462 and AgaP_AGAP004149

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_313033.3	Gene:	AgaP_AGAP004149 / 1273976	VectorBaseID:	AGAP004149	Length:	543	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	74/283 - (26%)
Similarity:	117/283 - (41%)	Gaps:	61/283 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGIPHNISERSVNAKL--------AQNPWM---AYLETPKG---FHCSGTLINHLFVLTAAHCVP 79
            ||:       |||.::        .|.|||   ||.....|   :.|:|:||.:..|:|.||||.
Mosquito   274 CGL-------SVNTRIIGGETEVPGQFPWMARLAYRNQTSGRVTYRCAGSLITNRHVITVAHCVT 331

  Fly    80 ---DDL-LITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRV 140
               |:| |:::|||:.......|   ..|...:|::.::....|..|:.....|||.:::|....
Mosquito   332 NLIDELQLVSIRLGDLECNAVTD---PRCSARYQDFAIEQIIPHESYDVPKYANDIALIKLRETT 393

  Fly   141 EYLNHIRPICIFASNRFQEPIDQLTWFTTTV---------WRETA--ANATSKVLRTMNIDRQPK 194
            |..|.|.|:|:        |.||...:...:         |..|:  :|..|..|:.:.:.....
Mosquito   394 ETYNIISPLCL--------PTDQYAPYALNLTGQLGIIAGWGSTSNRSNTPSPTLQWLRLPIVDT 450

  Fly   195 ETCSEIYGWN---------MTFEQICA-GNTLSQLCSTDSGAPQIRKMWHNGSDRYVQLGIAS-- 247
            ..|:..|...         ::..|:|| |......|..|||.|.:.:. .:..||:|.||:.|
Mosquito   451 AGCANAYARYSVNSRNPIIVSGNQMCAQGQENRDACQGDSGGPLMNEA-ISTRDRFVLLGLVSFG 514

  Fly   248 -RVKGQCQNSGILMDLLSYADWI 269
             |..|.....|:...:.:|.|||
Mosquito   515 PRTCGVSNFPGVYTRISAYIDWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	68/256 (27%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	66/254 (26%)
AgaP_AGAP004149	XP_313033.3	CLIP	47..92	CDD:288855
		Tryp_SPc	281..537	CDD:214473	67/267 (25%)
		Tryp_SPc	282..537	CDD:238113	67/266 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910