DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and CLIPB8

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_312743.1	Gene:	CLIPB8 / 1273740	VectorBaseID:	AGAP003057	Length:	405	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	76/291 - (26%)
Similarity:	133/291 - (45%)	Gaps:	63/291 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 EDCGIPHNISE--RSVNAKLAQNPWMAYLETPKGFH-----CSGTLINHLFVLTAAHCV------ 78
            :.|||...:::  ....|::.:.||||.|...:..:     |.|.||:..:|:||||||
Mosquito   126 DSCGIQSYVAKIRGGQLAEIDEFPWMAMLLYERDNNALTQGCGGALISRTYVITAAHCVTGKNFQ 190

  Fly    79 -PDDLLITVRLGEYNTKTKVDC--DNHL--CQE-----------PFQEYNVDMGFRHRYYNANDQ 127
             ....|..|||.|||..|..||  :|.|  |.:           |..||:.:         :::|
Mosquito   191 QTKGRLKFVRLREYNIHTNPDCVYENDLKDCSDDMIDLVPQAVIPHPEYDSE---------SSNQ 246

  Fly   128 TNDIGMLRLGRRVEYLNHIRPICIFASNRFQE---PIDQLT---WFTTTVWRET-AANATSKVLR 185
            .:||.::|:.:...:.:.:|.||:...| |:.   |..:|:   |..|.::::. ..:..|.:..
Mosquito   247 QHDIALIRIEQTPPFTDFLRSICLPEQN-FESSATPGKKLSVSGWGRTDIFKDNLGPDVLSPIKL 310

  Fly   186 TMNIDRQPKETCSEIY-GWNMTF--EQICAGNTLSQ-LCSTDSGAPQI-----RKMWH-NGSDRY 240
            .:::....:|.||:.: .|:...  .|:|||...:: .|:.|||:|.:     |.:|: .|   .
Mosquito   311 KLSLPYVEREKCSKTFRPWSFALGPGQMCAGGERAKDTCAGDSGSPLMSYDMKRAIWYITG---I 372

  Fly   241 VQLGI-ASRVKGQCQNSGILMDLLSYADWIK 270
            |.||: ...|:|.   .|:..::..|..|||
Mosquito   373 VSLGVRGCGVEGL---PGVYTNVHHYLPWIK 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	72/268 (27%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	69/265 (26%)
CLIPB8	XP_312743.1	CLIP	41..95	CDD:288855
		Tryp_SPc	136..399	CDD:214473	70/278 (25%)
		Tryp_SPc	139..400	CDD:238113	71/276 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910