DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	93/291 - (31%)
Similarity:	147/291 - (50%)	Gaps:	35/291 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IGI-----AVICCLW------RRVQGFQMLLEEDCGIPHNISER---SVNAKLAQNPWMAYL-ET 55
            :||     ..:||..      .|.:...:|..|.|| |: |.|:   .::|.|.|.||||.| :|
Mosquito   343 VGIEDEPRCAVCCQQEADSNNHRKRNLTLLDLEKCG-PY-IEEKIANGIDAILFQYPWMALLQDT 405

  Fly    56 PKGFHCSGTLINHLFVLTAAHCVPDDL-LITVRLGEYNTKTKVDCD--NHLCQEPFQEYNVDMGF 117
            ...|.|.|||||..:|||||||..:.| .|:|||||::.|:.:|||  ...|..|.|:..|:...
Mosquito   406 ELAFVCGGTLINKRYVLTAAHCFREKLSKISVRLGEFDLKSDIDCDKRGERCALPPQDIAVERTI 470

  Fly   118 RHRYYNANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANATSK 182
            :|:.|:|..:.|||.::||.....|..::.|||:..|...: .:.::  :..:.|..|..:.:|.
Mosquito   471 KHKDYSARHKVNDIALIRLASEASYNENVMPICLPVSPEMR-TVKEI--YYVSGWGLTENDTSSD 532

  Fly   183 VLRTMNIDRQPKETCSEIYG-----WNMTFEQICA-GNTLSQLCSTDSGAPQIRKMWHNGSDRYV 241
            ||:...:.:.|.:.|.::..     ..:..:|:|| |...:..||.|||.| ::.:..|.  |:|
Mosquito   533 VLQVGLLRQLPNDVCQQLLQRKDKYVTVNSDQMCAIGANRTDNCSGDSGGP-LKTVAVNA--RFV 594

  Fly   242 QLGIAS---RVKGQCQNSGILMDLLSYADWI 269
            |.|:.|   |..|:....|:...:.:|.|||
Mosquito   595 QYGVVSYGLRTCGKETAPGVYTRVENYIDWI 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	78/235 (33%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	76/233 (33%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	79/246 (32%)
		Tryp_SPc	385..625	CDD:238113	79/245 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810