DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and AgaP_AGAP013252

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_003436670.1	Gene:	AgaP_AGAP013252 / 11175997	VectorBaseID:	AGAP013252	Length:	597	Species:	Anopheles gambiae

Alignment Length:	336	Identity:	79/336 - (23%)
Similarity:	134/336 - (39%)	Gaps:	73/336 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSNFIIGIAVICCLW--RRVQGFQMLLEEDCGIPHNISERSVNA-KLAQN---------PWMAYL 53
            :..|:..|||.|.:.  |:......       :|....||.|.. .|.|:         ||...:
Mosquito     5 LRGFLALIAVFCAIGEVRKTNALDT-------VPLECGERKVKTIYLVQHGTETKEGHWPWHTAI 62

  Fly    54 ----ETPKGFHCSGTLINHLFVLTAAHCV--------PDDLLITV---RLGEYNTKTKVDCDNHL 103
                :|...:.|.|::::...:||||||:        .|.|.:.|   :|.|.:.::
Mosquito    63 YHREQTNFEYVCGGSILDRNTILTAAHCLYTSRGLIKLDQLSVQVGRNQLSEASVRS-------- 119

  Fly   104 CQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEP-IDQLTWF 167
                 ||::.:....|..::.|..|:||.:::|...:....:::|:|:::    .|| :|.:...
Mosquito   120 -----QEHHPEQLIVHPGFSPNSVTDDIALIKLATDITMTRYVQPVCLWS----LEPNLDLIVGR 175

  Fly   168 TTTV--WRETAANATSKVLRTMNIDRQPKETCSE----IYGWNMTFEQIC-AGNTLSQLCSTDSG 225
            ..||  :..|..:..|..||...|......||.|    :||..:|....| .|.|...:|:.|||
Mosquito   176 NGTVVGFGLTEHDRVSDYLRQAAIAVVDSWTCIESDRQVYGVTLTANMYCGGGKTGVSVCNGDSG 240

  Fly   226 APQIRKMWHNGSDRYVQLGIASRVK-----GQCQNS--GILMDLLSYADWIKRVVRQYGPSTDMN 283
            ...   .:.:|...||: |:.|.:.     |.|..:  .:..|:..|.|||.:.|   .|:....
Mosquito   241 GGM---FFEHGDTWYVR-GVVSFMPLRENVGLCDGTKYTVFTDVAKYRDWIGQNV---NPTLAST 298

  Fly   284 RSLKKWVDKIP 294
            |.....||..|
Mosquito   299 RPDPLLVDNSP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	61/253 (24%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	59/250 (24%)
AgaP_AGAP013252	XP_003436670.1	Tryp_SPc	47..287	CDD:214473	59/260 (23%)
		Tryp_SPc	48..287	CDD:238113	59/259 (23%)
		Tryp_SPc	334..575	CDD:214473
		Tryp_SPc	335..575	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910