DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and F11

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	277	Identity:	68/277 - (24%)
Similarity:	105/277 - (37%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VQGFQMLLEEDCGIPHNISERSVNAKL--------AQNPWMAYLETPKGFHCSGTLINHLFVLTA 74
            :.|:.:.|   |.: .|:....:|.::        .:.||...|...:|..|.|::|.:.::|||
Mouse   368 ISGYSLRL---CKM-DNVCTTKINPRVVGGAASVHGEWPWQVTLHISQGHLCGGSIIGNQWILTA 428

  Fly    75 AHC-----VPDDLLI---TVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDI 131
            |||     .|..|.:   .|...|.|..|..             :.|.....|..|...:...||
Mouse   429 AHCFSGIETPKKLRVYGGIVNQSEINEGTAF-------------FRVQEMIIHDQYTTAESGYDI 480

  Fly   132 GMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANA-TSKVLRTMNIDRQPKE 195
            .:|:|...:.|.:..||||: .|...:..:....|  .|.|..||... ....|:...:.....|
Mouse   481 ALLKLESAMNYTDFQRPICL-PSKGDRNAVHTECW--VTGWGYTALRGEVQSTLQKAKVPLVSNE 542

  Fly   196 TCSEIY-GWNMTFEQICAG--NTLSQLCSTDSGAP---QIRKMWHNGSDRYVQLGIASRVK--GQ 252
            .|...| ...:|.:.||||  ......|..|||.|   :...:||       .:||.|..:  ||
Mouse   543 ECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWH-------LVGITSWGEGCGQ 600

  Fly   253 CQNSGILMDLLSYADWI 269
            .:..|:..::..|.|||
Mouse   601 KERPGVYTNVAKYVDWI 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	63/239 (26%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	61/237 (26%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	2/10 (20%)
		Tryp_SPc	389..617	CDD:214473	61/250 (24%)
		Tryp_SPc	390..617	CDD:238113	61/249 (24%)
		Heparin-binding. /evidence=ECO:0000250	547..550		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910