DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	66/272 - (24%)
Similarity:	113/272 - (41%)	Gaps:	46/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGIPHNISERSVN---AKLAQNPWMAYLETPKG---FHCSGTLINHLFVLTAAHCVPDDLLITVR 87
            ||:...:..|.|.   |.:...||...|....|   :.|.|::|...:::||||||
Frog   255 CGLSTKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWIVTAAHCV--------- 310

  Fly    88 LGEYNTKT--KVDCDNHLCQEPFQE-YNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPI 149
            .|..:|.:  ||...:...|..:.. |.|:....|..|::..|..|:.:|:|...:.:..::||:
Frog   311 YGSTSTPSAFKVFAGSLTIQSYYSAGYTVERALVHPSYSSYTQIYDVALLKLTAALVFTTNLRPV 375

  Fly   150 CI------FASNRFQEPIDQLTWFTTTVWRETA-ANATSKVLRTMNIDRQPKETCSE--IYGWNM 205
            |:      :|..       |..|.:.  |..|| ..:.||.|...::......||::  :||..:
Frog   376 CLPNVGMPWAEG-------QPCWISG--WGTTAEGGSISKNLMAASVPIISSTTCNQAAVYGGAI 431

  Fly   206 TFEQICAG--NTLSQLCSTDSGAPQIRK---MWHNGSDRYVQLGIASRVKGQCQNSGILMDLLSY 265
            :...:|||  :..:..|..|||.|.:.|   :|....|.....|.|...|     .|:..::..:
Frog   432 SSTMMCAGYLSGGTDTCQGDSGGPLVTKTNSLWWLVGDTSWGYGCARAYK-----PGVYGNVTVF 491

  Fly   266 ADWIKRVVRQYG 277
            .:||...::.||
Frog   492 IEWIYSQMQTYG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	59/243 (24%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	57/240 (24%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	2/3 (67%)
		Tryp_SPc	265..498	CDD:238113	61/255 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910