DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	279	Identity:	65/279 - (23%)
Similarity:	109/279 - (39%)	Gaps:	62/279 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DCGIPHNISERSV---NAKLAQNPWMAYLETPKGFHCSGTLINHLFVLTAAHCVPDDL----LIT 85
            |||:......|.|   :|.:...||...|:......|.|::|...:::||||||..|.    |..
Frog   250 DCGLSTYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSLWK 314

  Fly    86 VRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPIC 150
            ..:|:....:..|.         ..|:||....|..|::...:|||.:::|...:.:.:..||:|
Frog   315 AFIGKIKMPSYYDS---------SAYSVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPVC 370

  Fly   151 IFASN---RFQE--PIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSE--IYGWNMTFE 208
            :  .|   :::|  |.....|.||     :...:.|.||:...:......||::  :|...:|..
Frog   371 L--PNYGMQWEEGQPCYISGWGTT-----SQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSS 428

  Fly   209 QICAGNTLSQL--CSTDSGAPQIRK-----------MWHNGSDRYVQLGIASRVKGQCQN---SG 257
            .||||.....:  |..|||.|.:.|           .|.:|                |.|   .|
Frog   429 MICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWGDG----------------CANVYRPG 477

  Fly   258 ILMDLLSYADWIKRVVRQY 276
            :..::..:..||...::.|
Frog   478 VYGNMTVFLQWIYLQMQMY 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	58/250 (23%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	56/247 (23%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	3/4 (75%)
		Tryp_SPc	261..489	CDD:238113	58/259 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910