DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33462 and tmprss3

DIOPT Version :9

Sequence 1:	NP_995844.2	Gene:	CG33462 / 2768841	FlyBaseID:	FBgn0053462	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	268	Identity:	72/268 - (26%)
Similarity:	111/268 - (41%)	Gaps:	55/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGI--PHNISERSVNAKLA---QNPWMAYLETPKGFH-CSGTLINHLFVLTAAHCVPDDLLI--- 84
            ||:  .:..|.|.|...::   |.||.|.| ..:|.| |.|:||...:::|||||| .|||.
Frog   232 CGLRPSYTSSARIVGGNVSAVGQWPWQASL-VFQGVHLCGGSLITPQWIVTAAHCV-YDLLYPEW 294

  Fly    85 -TVRLGEY-----NTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYL 143
             .|::|:.     :.:|.|         |.|:.     ..|..|.::...|||.::||.....:.
Frog   295 WRVQVGQVSQASESAQTAV---------PVQKI-----IYHSKYRSSTMANDIALIRLASPFTFN 345

  Fly   144 NHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANA-TSKVLRTMNIDRQPKETCSE--IYGWNM 205
            ..|:|||: .:.|...|..::.|.:.  |..|.... ||:.:....:.......|:.  |||..:
Frog   346 GSIQPICL-PNYREDFPEGKICWISG--WGATEEGGDTSQTMDYAGVPLISNRVCNTKYIYGGVI 407

  Fly   206 TFEQICAG------NTLSQLCSTDSGAP---QIRKMWHNGSDRYVQLGIASRVKGQCQNSGILMD 261
            ....:|||      :|    |..|||.|   :...:|.........:|.|.|.|     .|:...
Frog   408 KPSMVCAGFLEGGVDT----CQGDSGGPLACEDSNVWKLMGTTSWGIGCALRYK-----PGVYTR 463

  Fly   262 LLSYADWI 269
            :.|:.|||
Frog   464 ISSFLDWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	66/244 (27%)
CG33462	NP_995844.2	Tryp_SPc	48..269	CDD:214473	64/242 (26%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055	2/3 (67%)
		Tryp_SPc	244..472	CDD:238113	68/256 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910