Protein Alignment CG33461 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 62/307 - (20%)
• Similarity: 108/307 - (35%)
• Gaps: 86/307 - (28%)

  Fly    21 GLSIVRDQDTIEQLFNVNDIDQTLVEEDHGVAGVAIPKVHRLNF-AERKQQRQSKHLDLNELERK 84
            |:.|  |.||:|            ::.....|.:|..|.::.:. .|.|.:......|..:::|.
Human   461 GMQI--DADTLE------------IQRVKRAAKIASEKDYKRDLETEIKGKGMQVSTDTLDVQRA 511

  Fly    85 RRATEGSGGK-------SSTKGKECRT-----------RAGEKGHCTRYQSCKGPELKDNVWSVL 131
            :||:|.:..|       :..|||..:.           ||.|.....:|        ||....:|
Human   512 KRASEMASQKQYRKDLENEIKGKGMQVNVDIPDMLRAKRASEIYSQKKY--------KDEAEKML 568

  Fly   132 QHLCIV-------------EGISVGICCPDVVQDG----NGPEFSVRLP-----ATADSYDDVDG 174
            .:...|             :.|| .:...:.|:.|    |.||.. |:.     .::..|.:
Human   569 SNYSTVAVTPEIQRIKTTQQNIS-NVSYKEEVRAGTAVRNTPEIE-RVKKNQHNISSFQYKE--- 628

  Fly   175 LGDGPT--ARDATVRPEERGCGLSTKQLSKI--AG--GRPADSNEWPWMVALVSSRASFCGGVLI 233
                ||  |...|:.||......:.:|||.:  .|  ||....:..|.|..:..::.:.......
Human   629 ----PTYKATPVTMTPEIERVRRNQEQLSAVYYKGQLGRATALSVTPEMERVKKNQENISSVKYT 689

  Fly   234 TDRHVLTAAHCVM-------NLKLTQFVVRLGEYDFKQFNETRYRDF 273
            .|...:....||:       ::|..|..|.:.:| .:.|.:|:.|.|
Human   690 QDHKQMKGRPCVILDTPALRHVKEAQNHVSMVKY-HEDFEKTKGRGF 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	56/287 (20%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597
		Tryp_SPc	204..429	CDD:214473