Protein Alignment CG33461 and KLK7

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 72/291 - (24%)
• Similarity: 118/291 - (40%)
• Gaps: 68/291 - (23%)

  Fly     4 LEMKTIIAYLALFVLGVHGSSSVFLEENCGVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFLCA 68
            |.::.::..|||...|         ||..|      .|||:|.|...|.:||...|.:.....|.
Human     7 LPLQILLLSLALETAG---------EEAQG------DKIIDGAPCARGSHPWQVALLSGNQLHCG 56

  Fly    69 GSLINQWFVLTSAHCIEDDVELIARLGENNRDNDIDCENNRCLEATQEYNVDMLFKHRLYDPKDF 133
            |.|:|:.:|||:|||..:  |....||.:...:          ...|.......|:|..|..:..
Human    57 GVLVNERWVLTAAHCKMN--EYTVHLGSDTLGD----------RRAQRIKASKSFRHPGYSTQTH 109

  Fly   134 SNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVVDQI----------TWFKATGWG-LTSTDLNT 187
            .||:.:::|..:.               |:..:|.::          |....:||| .||.|:..
Human   110 VNDLMLVKLNSQA---------------RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTF 159

  Fly   188 KSSRVLMELNLYRRPRNDCARIFKQNFLSGQICAGNDDG--NLCRGDSGGPQGRYVLIFGMKRFV 250
            .|..:.:::.|. .|: ||.:::|....:..:|||..|.  |.|.||||||.        :.|..
Human   160 PSDLMCVDVKLI-SPQ-DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL--------VCRGT 214

  Fly   251 QMGIASFTYENCSKVS---ILTDVVRYGRWI 278
            ..|:.|:....|.:.:   :.|.|.::.:||
Human   215 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	62/252 (25%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	62/252 (25%)