Protein Alignment CG33461 and PRSS3

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 59/267 - (22%)
• Similarity: 108/267 - (40%)
• Gaps: 71/267 - (26%)

  Fly    41 KIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWFVLTSAHCIEDDVELIARLGENNRDNDIDC 105
            ||:.|........|:...|::.::| |.||||::.:|:::|||.:..:::  ||||:
Human    37 KIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQV--RLGEH-------- 90

  Fly   106 ENNRCLEATQEY-NVDMLFKHRLYDPKDFSNDIGMLRLERRVEYTYHIQPI------------CI 157
             |.:.||..::: |...:.:|..|:.....|||.:::|.........:..|            |:
Human    91 -NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTTPPAAGTECL 154

  Fly   158 FHHRRMQLVVDQITWFKATGWGLTST-------DLNTKSSRVLMELNLYRRPRNDCARIFKQNFL 215
            .                 :|||.|.:       :|....:.||.:.        :|...:.....
Human   155 I-----------------SGWGNTLSFGADYPDELKCLDAPVLTQA--------ECKASYPGKIT 194

  Fly   216 SGQICAGNDDG--NLCRGDSGGPQGRYVLIFGMKRFVQMGIASFTYENC---SKVSILTDVVRYG 275
            :...|.|..:|  :.|:.|||||    |:..|..:    |:.|:.: .|   ::..:.|.|..|.
Human   195 NSMFCVGFLEGGKDSCQRDSGGP----VVCNGQLQ----GVVSWGH-GCAWKNRPGVYTKVYNYV 250

  Fly   276 RWIKKVV 282
            .|||..:
Human   251 DWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	56/261 (21%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	58/263 (22%)