Protein Alignment CG33461 and PRSS2

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 65/275 - (23%)
• Similarity: 110/275 - (40%)
• Gaps: 73/275 - (26%)

  Fly    41 KIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWFVLTSAHCIEDDV------------ELIAR 93
            ||:.|........|:...|:: .|..|.||||::.:|:::.||.:..:            .:..|
Human    23 KIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly    94 LGENNRDNDIDCENNRCLEATQEY-NVDMLFKHRLYDPKDFSNDIGMLRLERRVEYTYHIQPICI 157
            |||:|.:         .||..::: |...:.:|..|:.:...|||.:::|.         .|..|
Human    87 LGEHNIE---------VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLS---------SPAVI 133

  Fly   158 FHHRRMQLV----------VDQITWFKATGWGLTSTDLNTKSSRVLM--ELNLYRRP---RNDCA 207
              :.|:..:          .:.:    .:|||      ||.||....  ||.....|   :.:|.
Human   134 --NSRVSAISLPTAPPAAGTESL----ISGWG------NTLSSGADYPDELQCLDAPVLSQAECE 186

  Fly   208 RIFKQNFLSGQICAGNDDG--NLCRGDSGGPQGRYVLIFGMKRFVQMGIASFTYENC---SKVSI 267
            ..:.....:...|.|..:|  :.|:||||||    |:..|..:    ||.|:.| .|   ::..:
Human   187 ASYPGKITNNMFCVGFLEGGKDSCQGDSGGP----VVSNGELQ----GIVSWGY-GCAQKNRPGV 242

  Fly   268 LTDVVRYGRWIKKVV 282
            .|.|..|..|||..:
Human   243 YTKVYNYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	62/269 (23%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	64/271 (24%)