DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33461 and CG33465

DIOPT Version :9

Sequence 1:	NP_995843.3	Gene:	CG33461 / 2768840	FlyBaseID:	FBgn0053461	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	90/280 - (32%)
Similarity:	135/280 - (48%)	Gaps:	31/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LALFVLGVHGSSSVFLEENCGVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWFV 77
            |||..|.:....:..|::.|. .|:.| :.||.........||||.::....|:|.|:|:::.||
  Fly     7 LALIGLVLCQGLAQLLDKKCH-DPKTS-ENINFNHGATETAPWMASIYKNNQFICDGTLVHKLFV 69

  Fly    78 LTSAHCIEDDVELIARLGENNRDNDIDCENNRCLEATQEYNVDMLFKHRLYDPKDFSNDIGMLRL 142
            ||:|.||..|.:|....|..|:..|.....|     .::|.|.:..:|..:.|.:..||||:|||
  Fly    70 LTAASCISKDSQLYVLFGMYNQYRDASQFFN-----NEQYGVAVALQHSNFRPNNGVNDIGLLRL 129

  Fly   143 ERRVEYTYHIQPICIFHHRRMQLVVDQIT------WFKATGWGLTSTDLNTKSSRVLMELNLYRR 201
            ...|.:..||:||||        ::|.:.      .|:..||....|:   .||:|...:.|.::
  Fly   130 YGEVTHYAHIRPICI--------ILDHVVKSAPFERFEGFGWQQQGTE---ASSQVRQTVYLSQK 183

  Fly   202 PRNDCAR---IFKQNFLSGQICAGNDDGNLCRGDSGGPQGRYVLIFGMKRF-VQMGIASFTYENC 262
            ...:|.|   :...|  .||.||||.|.:.||.:||.|. .....:|:|.. ||:|:.|:..|.|
  Fly   184 KPFECHRNGQLLPIN--EGQFCAGNRDRSFCRSNSGSPL-TADFTYGVKNITVQVGLVSYGSELC 245

  Fly   263 SKVSILTDVVRYGRWIKKVV 282
            |..|:.||||.:..||...|
  Fly   246 SPTSVYTDVVAFKDWIYNTV 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	79/246 (32%)
CG33461	NP_995843.3	Tryp_SPc	42..281	CDD:238113	81/248 (33%)
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	79/236 (33%)
		Tryp_SPc	46..261	CDD:214473	77/233 (33%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463376
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890