Protein Alignment CG33461 and KLK2

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 76/299 - (25%)
• Similarity: 118/299 - (39%)
• Gaps: 89/299 - (29%)

  Fly    25 SVFLEENC-GVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWFVLTSAHCIEDDV 88
            |:.|...| |.||.:..:|:.|........||...:::..:..|.|.|::..:|||:|||::.:.
Human     7 SIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS 71

  Fly    89 ELIARLGENNRDNDIDCENNRCLEATQEYNVDMLFKHRLYD-----------PKDFSNDIGMLRL 142
            ::  .||.:|.....|        ..|...|...|.|.||:           .:|.|:|:.:|||
Human    72 QV--WLGRHNLFEPED--------TGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRL 126

  Fly   143 ERRVEYTYHIQPI------------CIFHHRRMQLVVDQITWFKATGWGLTSTDLNTKSSRVLME 195
            ....:.|..::.:            |.                 |:|||             .:|
Human   127 SEPAKITDVVKVLGLPTQEPALGTTCY-----------------ASGWG-------------SIE 161

  Fly   196 LNLYRRPR-----------ND-CARIFKQNFLSGQICAGNDDG--NLCRGDSGGPQGRYVLIFGM 246
            ...:.|||           || |||.:.:......:|||...|  :.|.||||||    ::..|
Human   162 PEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGP----LVCNG- 221

  Fly   247 KRFVQMGIASFTYENCS---KVSILTDVVRYGRWIKKVV 282
               |..||.|:..|.|:   |.::.|.||.|.:|||..:
Human   222 ---VLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	67/276 (24%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	70/278 (25%)