DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33461 and CG10764

DIOPT Version :9

Sequence 1:	NP_995843.3	Gene:	CG33461 / 2768840	FlyBaseID:	FBgn0053461	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	98/275 - (35%)
Similarity:	137/275 - (49%)	Gaps:	19/275 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IAYLALFVLGV-HGSSSVFLEENCGVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFLCAGSLIN 73
            :|.|:|..|.| ......|||..||:..|  .||..|..|......|||.:...:.|.|.|::|:
  Fly     7 VALLSLLTLCVTENEHFKFLETPCGISTR--PKISGGDDAAEPNSIWMAAIFNSSDFQCGGTIIH 69

  Fly    74 QWFVLTSAHCIEDDVELIARLGENNRDNDIDCENNRCLEATQEYNVDMLFKHRLYDPKDFSNDIG 138
            ..|||::|||:....:|..|||..|.:           |....:.|..:|.|..:...::.||||
  Fly    70 MRFVLSAAHCLVRGYDLYVRLGARNIN-----------EPAAVHTVINVFVHHDFIASEYRNDIG 123

  Fly   139 MLRLERRVEYTYHIQPICIFHHRRMQLVVDQITWFKATGWGLTSTDLNTKSSRVLMELNLYRRPR 203
            :|:|...:.||..:||||||....::..|:::..|:|.|||    :.|.|.|.:|..:.|....|
  Fly   124 LLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWG----NRNGKLSIMLQTIYLLHLKR 184

  Fly   204 NDCARIFKQNFLSGQICAGNDDGNLCRGDSGGPQGRYVLIFGMKRF-VQMGIASFTYENCSKVSI 267
            |:|.|....|..|.|||||..:|:.||||||||....:|....|.: ||:||.||....|..|.:
  Fly   185 NECKRKLNFNLNSRQICAGTKNGDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPECRGVGV 249

  Fly   268 LTDVVRYGRWIKKVV 282
            .|||..|..||...:
  Fly   250 YTDVTSYVDWISSTI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	85/237 (36%)
CG33461	NP_995843.3	Tryp_SPc	42..281	CDD:238113	86/239 (36%)
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	85/237 (36%)
		Tryp_SPc	38..263	CDD:238113	86/239 (36%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463372
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
	7	6.840