DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33461 and spirit

DIOPT Version :9

Sequence 1:	NP_995843.3	Gene:	CG33461 / 2768840	FlyBaseID:	FBgn0053461	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	73/260 - (28%)
Similarity:	117/260 - (45%)	Gaps:	42/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IINGTPARLGRYPWMAFL------HTPTYFLCAGSLINQWFVLTSAHCIE--DDVELIARLGENN 98
            ::.|.|.|...:|:||.|      ....|:.|.|:||...||||:|||.:  .:.....|||
  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLG--- 193

  Fly    99 RDNDIDCENNRCLEATQEYNVDMLFKHRLYDPKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRM 163
                   .:|..|...::.::..:..|..|......|||.:|.||...:  ..::|.||:..:.:
  Fly   194 -------GDNLTLTEGEDISIRRVIIHPDYSASTAYNDIALLELETAAK--PELKPTCIWTQKEV 249

  Fly   164 QLVVDQITWFKATGWGLTSTDLNTKSSRVLMELNLYRRPRNDCARIFK-----QNFLSGQICAGN 223
                 ..|...|.|:|.||  ....||..|:::.|......:|...::     |..|..|:|||:
  Fly   250 -----TNTLVTAIGYGQTS--FAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGD 307

  Fly   224 DDG--NLCRGDSGGPQGRYVLIFGMKRFVQMGIASFTYENCSK--VSILTDVVRYGRWIKKVVDW 284
            ..|  :.|:||||||   .::..|:..:| :||.|.. :.|:.  .|:.|.|..:..||:.:| |
  Fly   308 ITGERDTCQGDSGGP---LLMQDGLLGYV-VGITSLG-QGCASGPPSVYTRVSSFVDWIEGIV-W 366

Fly 285 284
Fly 367 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	69/252 (27%)
CG33461	NP_995843.3	Tryp_SPc	42..281	CDD:238113	71/255 (28%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	71/255 (28%)
		Tryp_SPc	132..361	CDD:214473	69/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940