Protein Alignment CG33461 and F10

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 72/260 - (27%)
• Similarity: 121/260 - (46%)
• Gaps: 49/260 - (18%)

  Fly    41 KIINGTPARLGRYPWMAFL-HTPTYFLCAGSLINQWFVLTSAHCIEDDVELIARLGENNRDNDID 104
            :|:.|...:.|..||.|.| :......|.|::::::::||:|||:........|:|:.|.:.:
Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQE-- 296

  Fly   105 CENNRCLEATQEYNVDMLFKHRLYDPKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVVDQ 169
             |..   ||..|  |:::.||..:..:.:..||.:|||:..:.:..::.|.|:          .:
Human   297 -EGG---EAVHE--VEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACL----------PE 345

  Fly   170 ITWFKAT----------GWGLTSTDLNTKSSRVLMELNLYRRPRNDC----ARIFKQNFLSGQIC 220
            ..|.::|          |:|.|. :...:|:|:.| |.:....||.|    :.|..||    ..|
Human   346 RDWAESTLMTQKTGIVSGFGRTH-EKGRQSTRLKM-LEVPYVDRNSCKLSSSFIITQN----MFC 404

  Fly   221 AGND--DGNLCRGDSGGPQGRYVLIFGMKRFVQMGIASFTYENCS---KVSILTDVVRYGRWIKK 280
            ||.|  ..:.|:||||||   :|..|....|| .||.|:. |.|:   |..|.|.|..:.:||.:
Human   405 AGYDTKQEDACQGDSGGP---HVTRFKDTYFV-TGIVSWG-EGCARKGKYGIYTKVTAFLKWIDR 464

  Fly   281  280
            Human   465  464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	70/256 (27%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	72/257 (28%)
		O-glycosylated at one site	476..485