Protein Alignment CG33461 and F7

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 88/304 - (28%)
• Similarity: 136/304 - (44%)
• Gaps: 66/304 - (21%)

  Fly    14 ALFVLGVHGSSSVFLEENCGVVPRLSY--------KIINGTPARLGRYPWMAFLHTPTYFLCAGS 70
            :|...||  |.:..:|..||.:|.|..        :|:.|.....|..||...|......||.|:
Human   208 SLLADGV--SCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGT 270

  Fly    71 LINQWFVLTSAHC---IEDDVELIARLGENN-RDNDIDCENNRCLEATQEYNVDMLFKHRLYDPK 131
            |||..:|:::|||   |::...|||.|||:: .::|.|.::.|         |..:.....|.|.
Human   271 LINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRR---------VAQVIIPSTYVPG 326

  Fly   132 DFSNDIGMLRLERRVEYTYHIQPICI----FHHRRMQLVVDQITWFKATGWGLT----STDLNTK 188
            ..::||.:|||.:.|..|.|:.|:|:    |..|.:..|    .:...:|||..    :|.|.
Human   327 TTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFV----RFSLVSGWGQLLDRGATALE-- 385

  Fly   189 SSRVLMELNLYRRPRNDCARIFKQ-----NFLSGQICAGNDDG--NLCRGDSGGP-----QGRYV 241
                ||.||:.|....||.:..::     |......|||..||  :.|:||||||     :|.:.
Human   386 ----LMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWY 446

  Fly   242 LIFGMKRFVQMGIASFTYENCSKV---SILTDVVRYGRWIKKVV 282
            |         .||.|:. :.|:.|   .:.|.|.:|..|::|::
Human   447 L---------TGIVSWG-QGCATVGHFGVYTRVSQYIEWLQKLM 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	77/263 (29%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	3/9 (33%)
		Tryp_SPc	242..478	CDD:238113	78/264 (30%)