Protein Alignment CG33461 and KLK8

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 69/250 - (27%)
• Similarity: 112/250 - (44%)
• Gaps: 33/250 - (13%)

  Fly    41 KIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWFVLTSAHCIEDDVELIARLGENNRDNDIDC 105
            |::.|...:....||.|.|......||.|.|:...:|||:|||.:.  :...|||:::..|....
Human    77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKP--KYTVRLGDHSLQNKDGP 139

  Fly   106 ENNRCLEATQEYNVDMLFKHRLY---DPKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVV 167
            |        ||..|.....|..|   |.:|.::|:.:|:|..:......::||.:..|....  .
Human   140 E--------QEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP--G 194

  Fly   168 DQITWFKATGWG-LTSTDLNTKSSRVLMELNLYRRPRNDCARIFKQNFLSGQICAGNDDG-NLCR 230
            .:.|   .:||| :||...|...:....|:.::  |:..|...:......|.:|||:..| :.|:
Human   195 QKCT---VSGWGTVTSPRENFPDTLNCAEVKIF--PQKKCEDAYPGQITDGMVCAGSSKGADTCQ 254

  Fly   231 GDSGGPQGRYVLIFGMKRFVQMGIASFTYENC---SKVSILTDVVRYGRWIKKVV 282
            ||||||    ::..|    ...||.|:..:.|   .|..:.|::.||..||||::
Human   255 GDSGGP----LVCDG----ALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	65/244 (27%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	65/244 (27%)