Protein Alignment CG33461 and KLK11

DIOPT Version :10

• Sequence 1: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 75/313 - (23%)
• Similarity: 120/313 - (38%)
• Gaps: 69/313 - (22%)

  Fly     2 PCLEMKTIIAYLALFVLGVHGSSSVFLEENCGVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFL 66
            |...|:.:...|.....|:.|..:               :||.|...:....||.|.|...|..|
Human    29 PLQAMRILQLILLALATGLVGGET---------------RIIKGFECKPHSQPWQAALFEKTRLL 78

  Fly    67 CAGSLINQWFVLTSAHCIEDDVEL-----------------------IARLGENNRDNDIDCENN 108
            |..:||...::||:|||::..|.|                       |..||::|...:..||..
Human    79 CGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQT 143

  Fly   109 RCLEATQEYNVDMLFKHRLYD----PKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVVDQ 169
            |  .||:.      |.|..::    .||..|||.::::...|..|:.::|:.:     ....|..
Human   144 R--TATES------FPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL-----SSRCVTA 195

  Fly   170 ITWFKATGWGLTSTDLNTKSSRVLMELNLYRRPRNDCARIFKQNFLSGQICAGNDDG--NLCRGD 232
            .|....:|||.||:. ..:....|...|:.......|...:..|.....:||...:|  :.|:||
Human   196 GTSCLISGWGSTSSP-QLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGD 259

  Fly   233 SGGPQGRYVLIFGMKRFVQMGIASFTYENCS---KVSILTDVVRYGRWIKKVV 282
            ||||     |:....   ..||.|:..:.|:   |..:.|.|.:|..||::.:
Human   260 SGGP-----LVCNQS---LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETM 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	68/268 (25%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	68/268 (25%)