DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33461 and CG42694

DIOPT Version :9

Sequence 1:	NP_995843.3	Gene:	CG33461 / 2768840	FlyBaseID:	FBgn0053461	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	89/303 - (29%)
Similarity:	138/303 - (45%)	Gaps:	66/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MKTIIAY-LALFVLGVHGSSSVFLEENCGVVPRLSYKIINGTPARLGRYP---WMAFLHTPTYFL 66
            |:|:.|: |.|.||..|.:|. ||::.||.      .|.|.:..:| |.|   |:|.:...|:.|
  Fly     1 MQTLFAWLLMLTVLQSHVNSK-FLDDYCGA------PISNQSITKL-RQPQAGWLAHISNGTHVL 57

  Fly    67 CAGSLINQWFVLTSAHCIEDDVELIARLGENNRDNDIDCENNRCLEATQE---YNVD--MLFKHR 126
            |:||||::.|||::|.||:...:|..:||.:|              ||:.   |.|.  ::..|
  Fly    58 CSGSLISKQFVLSAAQCIDVHGKLFVQLGVSN--------------ATKSPHWYTVSNVVIPSH- 107

  Fly   127 LYDPKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVVDQITWFKATGWGLTSTDLNTKSSR 191
              ..|....|||:|:|.:.|:|...:.||||..:.....:|..:..|..:.|  .|.:.|.::.
  Fly   108 --SGKRLQRDIGLLKLSQSVDYNDFVYPICIALNTNTLDMVKILQNFTTSAW--LSKNKNPQTI- 167

  Fly   192 VLMELNLYRRPRNDCARIFKQNFLSGQICAGN-DDGNLCRGDSGGP------QGRYV---LIFGM 246
            ||.:|:     |:.|......|....:|||.: ...|.|..|||..      ||..:   ::||:
  Fly   168 VLSQLS-----RDRCKLNLSGNVTPKEICAASLQRNNSCFIDSGSALTQPIIQGSNIVREMLFGI 227

  Fly   247 KRFVQMGIASFTYEN----CSKVSILTDVVRYGRWIKKVVDWY 285
            :.:|          |    ||:.:|..||.....||:.||..|
  Fly   228 RGYV----------NGRSWCSEPAIYIDVAECVGWIETVVQQY 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	71/258 (28%)
CG33461	NP_995843.3	Tryp_SPc	42..281	CDD:238113	73/260 (28%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	68/244 (28%)
		Tryp_SPc	46..253	CDD:214473	66/241 (27%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840