DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fs and Tmeff1

DIOPT Version :9

Sequence 1:	NP_652376.2	Gene:	Fs / 2768836	FlyBaseID:	FBgn0259878	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_075409.1	Gene:	Tmeff1 / 63845	RGDID:	62005	Length:	373	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	56/218 - (25%)
Similarity:	83/218 - (38%)	Gaps:	60/218 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   572 GTDGRTYN-TECQLRK---RACRTNNAQLEVAYRGHCKNSCSGVHCLNGLTCVEDQYLMPHCIAC 632
            |..|::.| :|..||:   |||..::.:    |.|.||....|:.|                 ||
  Rat    49 GGRGKSINCSELNLRESDIRACDESSCK----YGGVCKEDGDGLKC-----------------AC 92

  Fly   633 RIECPWDNLDVDSSGYDERQAVCGVDGKTYRSACDINRMICKIGRSIAVAYPGPCRAGRVSCA-- 695
            :.:|..:.:           .|||.:|.||::.|.:.|..||..:.|.|...|||.:...|.:
  Rat    93 QFQCHTNYI-----------PVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGE 146

  Fly   696 -------------DIKCGP---KDNCLVDLQTRQPRCVTCRYKCPRKQQRPVHKICGYNNQTYNS 744
                         ..||||   |..|  |.......|| |...|......||   |..:..:||:
  Rat   147 GEEEGSGAGAHRKHSKCGPCKYKAEC--DEDAENVGCV-CNIDCSGYSFNPV---CASDGSSYNN 205

  Fly   745 WCEMHKHSCESRYFIGVKSQGSC 767
            .|.:.:.||..:..|.::..|.|
  Rat   206 PCFVREASCIRQEQIDIRHLGHC 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fs	NP_652376.2	KAZAL	564..604	CDD:197624	11/35 (31%)
		KAZAL_FS	654..687	CDD:238052	13/32 (41%)
		KAZAL_FS	723..767	CDD:238052	11/43 (26%)
Tmeff1	NP_075409.1	KAZAL	92..136	CDD:197624	15/54 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..162		1/21 (5%)
		KAZAL	182..228	CDD:197624	13/49 (27%)
		PHA02887	<268..304	CDD:165214
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..373
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810