DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fs and Tmeff2

DIOPT Version :9

Sequence 1:	NP_652376.2	Gene:	Fs / 2768836	FlyBaseID:	FBgn0259878	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_062764.1	Gene:	Tmeff2 / 56363	MGIID:	1861735	Length:	374	Species:	Mus musculus

Alignment Length:	226	Identity:	57/226 - (25%)
Similarity:	82/226 - (36%)	Gaps:	68/226 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   569 PVCGTDGRTYNTECQLRKRACRTNNAQLEVAYRGHC-----KNSCSGVH---------------- 612
            ||||::|.:|..||.||:.||: ..:::.|...|.|     ..|..|||
Mouse   101 PVCGSNGESYQNECYLRQAACK-QQSEILVVSEGSCATDTGSGSGDGVHEGSGETSQKETSTCDI 164

  Fly   613 CLNGLTCVEDQYLMPHCIACRIECPWDNLDVDSSGYDERQAVCGVDGKTYRSACDINRMICKIGR 677
            |..|..|.||...: .|: |.|:|...|.:          .:|..|||:|.:||.|....|:...
Mouse   165 CQFGAECDEDAEDV-WCV-CNIDCSQTNFN----------PLCASDGKSYDNACQIKEASCQKQE 217

  Fly   678 SIAVAYPGPCRAGRVSCADIKCGPKDNCLVDLQTRQPRCVTCRY----KCPRKQQRPVHKICGYN 738
            .|.|...|.|              :||.....::.........|    ....:..|..|..|
Mouse   218 KIEVMSLGRC--------------QDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPC--- 265

  Fly   739 NQTYNSWCEMH---KHS---------CESRY 757
            .:.||.:| ||   :||         |::.|
Mouse   266 PEHYNGFC-MHGKCEHSINMQEPSCRCDAGY 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fs	NP_652376.2	KAZAL	564..604	CDD:197624	14/34 (41%)
		KAZAL_FS	654..687	CDD:238052	12/32 (38%)
		KAZAL_FS	723..767	CDD:238052	12/47 (26%)
Tmeff2	NP_062764.1	KAZAL_FS	95..135	CDD:238052	14/34 (41%)
		KAZAL	181..227	CDD:197624	16/56 (29%)
		PHA02887	<236..301	CDD:165214	13/64 (20%)
		Required for shedding. /evidence=ECO:0000250	303..320
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	353..374
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810